Genomics and Bioinformatics Core Facility

An Introduction to the Genomics and Bioinformatics Core Facility

The Genomics & Bioinformatics Core Facility (GBCF) at the University of Notre Dame provides cutting-edge sequencing and data analysis solutions for a wide range of applications, including metagenomics, transcriptomics, epigenomics, population genomics, and cancer genomics, in both model and non-model systems. Supporting research in human disease, pathogen and vector genomics, and environmental biology, GBCF serves Notre Dame investigators, external academic partners, and industry collaborators. As an Indiana CTSI-approved core facility, we offer access to Illumina sequencing, single-cell and spatial transcriptomics, and tailored bioinformatics workflows to meet the needs of a diverse research community.

Mission Statement

The mission of the Genomics and Bioinformatics Core Facility (GBCF) at Notre Dame is to advance research and scholarship by offering access to genomics technologies, bioinformatics analysis, and selective training programs.

Key aspects of the GBCF's mission include:

• Providing advanced genomics technologies and knowledge to support scholarly endeavors across diverse disciplines.
• Empowering researchers with access to the latest sequencing platforms like Illumina and specialized methodologies such as single-cell analysis and spatial transcriptome profiling.
• Facilitating robust bioinformatics analysis through customized pipelines tailored to specific research objectives and experimental designs.
• Supporting knowledge dissemination and empowerment through comprehensive training programs and consultation services.

Through these efforts, the GBCF aims to enable researchers to explore biological phenomena with precision, resolve disease mechanisms, and uncover novel therapeutic targets. Ultimately, the GBCF plays a pivotal role in fostering collaboration, promoting academic excellence, and advancing scientific discovery within the Notre Dame community and beyond.

Services

The Genomics & Bioinformatics Core Facility at Notre Dame provides comprehensive genomics and bioinformatics support for a wide range of research applications. Genomics services include project consultation, next-generation Illumina sequencing, standard and custom library construction methods, 10X single-cell sequencing, as well as Sanger sequencing and fragment analysis. Bioinformatic services focus on the analysis of genomic datasets, including custom software design, data management, and access to high-performance biocomputing resources. Our team is available to support your project from experimental design through data interpretation.

Let Us Help You Get a New Project Started 

Internal Users: To request a project consultation or service, please visit the  “request services” tab and choose from the appropriate category.

External User: To request a project consultation or service, please visit our main website's contact form by clicking here and a staff member will contact you within 48 hours.  

Need Help or Have Questions About an Existing Project?

For project-related or technical support, please contact one of our team members below.

Leadership

Michael Pfrender, Ph.D., Director of Genomics and Bioinformatics, Professor
Melissa Stephens, M.S., Assistant Director

Bahart Mishra, Ph.D., Principal Bioinformatician, Assistant Professor

 Locations and Hours of Operation

Links and Resources

Additional information about our services can be found on our Genomics and Bioinformatics Core Facility Website.

Contacts

Map

https://tour.nd.edu/locations/mccourtney-hall/