Chemical Synthesis and Drug Discovery Facility

Overview of Services

The facility supports translational biomedical research by providing expertise that enables the preparation of small molecules for use in hit verification, lead development, and midsize scale-up. In addition, the core supports the preparation of biological probes (affinity, fluorescently tagged, etc.), active pharmaceutical agents as experimental controls, small chemical libraries for structure-activity relationships and the optimization pharmacoogical properties. This shared user research core is also charged with organizational oversight of the products of past, current, and future chemical synthesis to create a university compound collection with currently 20,000 unique chemical entities.                                                                                                        

Services:

Chemical Synthesis/Consultation

LCMS Services

Compound Purfication

Compound Registration and Storage

Project Management Development(minimum 5 hours)

Equipment and Technology:

LCMS

Compound Purfication

Yamazen Flash Chromotography                                                                                                                                                                                                                                                                                 

Leadership

Location and hours of operation

Links and Resources

1. https://drugdiscovery.nd.edu/services/
2. https://research.nd.edu/our-research/facilities-and-resources/

Contacts