Chemical Synthesis and Drug Discovery Facility

Overview of Services

The facility supports translational biomedical research by providing expertise that enables the preparation of small molecules for use in hit verification, lead development, and midsize scale-up. In addition, the core supports the preparation of biological probes (affinity, fluorescently tagged, etc.), active pharmaceutical agents as experimental controls, small chemical libraries for structure-activity relationships and the optimization pharmacoogical properties. This shared user research core is also charged with organizational oversight of the products of past, current, and future chemical synthesis to create a university compound collection with currently 20,000 unique chemical entities.                                                                                                        


Chemical Synthesis/Consultation

LCMS Services

Compound Purfication

Compound Registration and Storage

Project Management Development(minimum 5 hours)

Equipment and Technology:


Compound Purfication

Yamazen Flash Chromotography                                                                                                                                                                                                                                                                                 


Brandon Ashfeld, PhD Facility Director 574-631-1727

Location and hours of operation

Hours Location

Monday - Friday 

8AM - 5PM

310 McCourtney Hall

Notre Dame, IN 46556

Links and Resources



Name Role Phone Email Location
Brandon Ashfeld, PhD
Facility Director
305 McCourtney Hall

Service list

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Services (10)